
Very minor spoilers: first episode or so
The show takes place in Boston, Massachusetts, following the cases of the Fringe Division, a division of the FBI dedicated to solving crimes that, as the name implies, are scientific with dubious scientific procedures.
The main character is Olivia Dunham, who, after her lover dies, joins the Fringe Division. She is assisted by Peter Bishop, a civilian consultant for the Fringe Division, and former con-man. He is also the guardian of his father, Walter Bishop. Walter Bishop is a "mad scientist" who, while being eccentric at times, is always a big help to the Fringe Division whenever there is a new case.
I feel reluctant to say a lot about this show, since it's fairly new, and it would just be awful for me to spoil it for anyone who hasn't seen it yet, or is watching it right now. The show is at its 3rd season, and the plot is already very intricately woven. I will make posts per season finale, summarizing and giving my opinion about the whole season, most likely when season 3 ends.